Jean-François Rupprecht (CPT)
Out-of-equilibrium Mechanics (OM)
February 2019 - present | CENTURI group leader
2015 - 2018 | Postdoctoral fellow, Mechanobiology Institute, NUS (Singapore)
2014 - 2015 | Postdoctoral fellow, Laboratoire de Physique Statistique - ENS Paris
2012 - 2014 | Diploma thesis research in physics, Université Pierre et Marie Curie (Paris, France)
2009 - 2012 | M.S. Degree in physics, ENS Paris
Luminy campus, Marseille (France)
About his research
The objective of the OM team is to develop generic theoretical frameworks that have a predictive value and which can inspire new experiments in biophysics. Current subjects - associated to post-doc and PhD openings - aim at answering questions inspired by embryonic development, that we model as a fluctuating hydrodynamics problem: within developing embryonic tissues, how do robust flow patterns emerge in order to shape functional organs with well-controlled structures? What makes these patterns robust to cell-scale fluctuations? Conversely, could cell-scale fluctuations play a shaping role during embryogenesis?
We think of these questions as exciting opportunities to explore the relation between force generation processes at the microscopic scale (e.g. molecular motor contraction at the cellular scale) and emerging mechanical properties at the macroscopic scale (e.g. embryonic tissue), with the objective of gaining a new perspective on what drives the emergence of mechanical pattern either in vivo (embryogenesis) or in artificial systems (such as cell monolayers, cancer spheroids or organoids).