The PLM series started 15 years ago from an interest to promote the interface between the Life and Physical Sciences in Cambridge. Over the years, PLM has grown from a local meeting to a popular international event that attracts interdisciplinary scientists from all around the world. Since 2018, a new partner has joined PLM: the Turing Centre for Living Systems (CENTURI, Aix-Marseille University, France) and the 2022 PLM symposium will take place in Marseille from September 27 to 28 and in Cambridge, from Septembrer 29 to 30.