Shao-Zhen Lin

Hydrodynamic instabilities in curved environment: from cell-cell membrane dynamics to embryonic tissue flows

Team: Out-of-equilibrium Mechanics (OM) team (CPT - CENTURI)

His background

October 2019 - present | CENTURI Postdoctoral fellow

2013 - 2019 | PhD in Biomechanics - Institute of Biomechanics and Medical Engineering, Department of Engineering Mechanics, Tsinghua University (Beijing, China)

2009 - 2013 | BSc & MSc in Engineering Mechanics - Department of Engineering Mechanics, Tsinghua University (Beijing, China)

About his postdoctoral project

Epithelia tissues, which form the outer cellular layer of organs, are intrinsically curved surfaces. Yet, so far, most models for epithelial tissue flows are focused on flat geometries. New in vitro and in vivo   experiments are questioning the role of curvature on the dynamics of epithelial tissue. Here, our objective is to derive a hydrodynamic theory that is predictive of both cellular forms and of embryonic tissue flows within curved environment. In particular, our focus is to derive analytical criteria on the value of mechanical parameters which can lead to spontaneous flow instabilities.

 
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